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cd137 protein  (Sino Biological)


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    Sino Biological cd137 protein
    Cd137 Protein, supplied by Sino Biological, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+4+1bb/Human+4-1BB+CD137+Protein/us12479921-805-1-5
    Average 93 stars, based on 2 article reviews
    cd137 protein - by Bioz Stars, 2026-10
    93/100 stars

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    Concentration Assay:

    Article Title: Computational design of bifaceted protein nanomaterials
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were diluted to a concentration of 2.5 μg/ml in the kinetic buffer and loaded onto streptavidin-coated biosensors (SAForteBio). ..

    Article Title: Computational design of bifaceted protein nanomaterials with tailorable properties
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were diluted to a concentration of 2.5 μg/mL in the kinetics buffer and loaded onto streptavidin-coated biosensors (SAForteBio). ..

    Article Title: Computational design of bifaceted protein nanomaterials
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were incubated with Nile Red and Purple particles, respectively, at a concentration of 10 μg of receptor per 1 mg of Spherotech streptavidin particles, with gentle rotation for 30 min. ..

    Article Title: Computational design of bifaceted protein nanomaterials.
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were incubated with Nile Red and purple particles, respectively, at a concentration of 10 μg of receptor per 1 mg of Spherotech streptavidin particles, with gentle rotation for 30 min. ..

    Article Title: Computational design of bifaceted protein nanomaterials.
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were diluted to a concentration of 2.5 μg ml−1 in the kinetic buffer and loaded onto streptavidin-coated biosensors (SAForteBio). ..

    Flow Cytometry:

    Article Title: Computational design of bifaceted protein nanomaterials.
    Article Snippet: .. Coating streptavidin-coated fluorescent Nile Red and purple particles with biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) was performed following the same procedure as the flow cytometry experiments. ..

    Article Title: Computational design of bifaceted protein nanomaterials with tailorable properties
    Article Snippet: .. Coating streptavidin-coated fluorescent Nile Red and Purple particles with biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) was performed following the same procedure as for the flow cytometry experiments. ..

    Article Title: Computational design of bifaceted protein nanomaterials
    Article Snippet: .. Coating streptavidin-coated fluorescent Nile Red and purple particles with biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) was performed following the same procedure as for the flow cytometry experiments. ..

    Incubation:

    Article Title: Computational design of bifaceted protein nanomaterials
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were incubated with Nile Red and Purple particles, respectively, at a concentration of 10 μg of receptor per 1 mg of Spherotech streptavidin particles, with gentle rotation for 30 min. ..

    Article Title: Computational design of bifaceted protein nanomaterials.
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were incubated with Nile Red and purple particles, respectively, at a concentration of 10 μg of receptor per 1 mg of Spherotech streptavidin particles, with gentle rotation for 30 min. ..

    Gentle:

    Article Title: Computational design of bifaceted protein nanomaterials
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were incubated with Nile Red and Purple particles, respectively, at a concentration of 10 μg of receptor per 1 mg of Spherotech streptavidin particles, with gentle rotation for 30 min. ..

    Article Title: Computational design of bifaceted protein nanomaterials.
    Article Snippet: .. Biotinylated human IL-2Rβ (Acro Biosystems, ILB-H82E3) and human 4-1BB (Sino Biological, 10041-H27H-B) were incubated with Nile Red and purple particles, respectively, at a concentration of 10 μg of receptor per 1 mg of Spherotech streptavidin particles, with gentle rotation for 30 min. ..



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    Phenotypic modulation of T cells and enhanced priming by anti-CTLA4-NF (A) PaCMAP plot of NeoRED-P patient tumor-infiltrating CD8 T cells by CyTOF. Clusters were derived from FlowSOM. (B) Pseudocolor density plots of CD8 T cells in PaCMAP space stratified by treatment group. (C) Expression of CD39 and 4-1BB by geometric MI on CD8 T cells as represented by color mapping on PaCMAP plot. (D) Violin plot representing frequency of manually gated CD39 + 4-1BB + CD8 T cells as a percentage of all CD8 T cells stratified by treatment group. Untreated, n = 7; ADT, n = 8; ADT + anti-CTLA4-NF, n = 8. Single patient with MSI hi status called out in plot. For this and all violin plots to follow, solid lines denote group medians, while dashed lines denote quartiles. (E) PaCMAP plot of NeoRED-P patient tumor-infiltrating CD4 + FoxP3 - Tconv cells by CyTOF. Clusters were derived from FlowSOM. (F) Pseudocolor density plots of CD4 Tconv cells in PaCMAP space stratified by treatment group. (G) Expression of CD39 and 4-1BB by geometric MI on CD4 Tconv as represented by color mapping on PaCMAP plot. (H) Violin plot representing frequency of manually gated CD39 + 4-1BB + CD4 Tconv cells as a percentage of all CD8 T cells stratified by treatment group. Untreated, n = 7; ADT, n = 8; ADT + anti-CTLA4-NF, n = 8. Single patient with MSI hi status called out in plot. (I) PaCMAP plot of MycCaP-infiltrating CD8 T cells by 45-parameter flow cytometry in response to ADT, ADT + anti-CTLA4 (ND), or ADT + anti-CTLA4 (D). Clusters were derived from FlowSOM. (J) Pseudocolor density plots of CD8 T cells in PaCMAP space stratified by treatment group. (K) Expression of CD39 and 4-1BB by geometric MFI on CD8 T cells as represented by color mapping on PaCMAP plot. (L) Violin plot representing frequency of manually gated CD39 + 4-1BB + CD8 T cells as a percentage of all CD8 T cells stratified by treatment group. (M) Biaxial plots representing expression of CD44 and Ki67 on CD8 T cells in tumor-draining lymph nodes of mice shown in (I–L). (N) Biaxial plots representing expression of CD44 and Ki67 on CD4 + FoxP3 − Tconv cells in tumor-draining lymph nodes of mice shown in (L–O). (O) Violin plots representing frequencies of CD44 + Ki67 + CD8 and CD4 Tconv cells as a percentage of parent populations stratified by treatment group. Two-tailed Welch’s t test was used to assess statistical significance. All murine data shown are n = 7 per group and representative of two independent experiments each for survival and immune profiling studies.

    Journal: Cell Reports Medicine

    Article Title: Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial

    doi: 10.1016/j.xcrm.2026.102638

    Figure Lengend Snippet: Phenotypic modulation of T cells and enhanced priming by anti-CTLA4-NF (A) PaCMAP plot of NeoRED-P patient tumor-infiltrating CD8 T cells by CyTOF. Clusters were derived from FlowSOM. (B) Pseudocolor density plots of CD8 T cells in PaCMAP space stratified by treatment group. (C) Expression of CD39 and 4-1BB by geometric MI on CD8 T cells as represented by color mapping on PaCMAP plot. (D) Violin plot representing frequency of manually gated CD39 + 4-1BB + CD8 T cells as a percentage of all CD8 T cells stratified by treatment group. Untreated, n = 7; ADT, n = 8; ADT + anti-CTLA4-NF, n = 8. Single patient with MSI hi status called out in plot. For this and all violin plots to follow, solid lines denote group medians, while dashed lines denote quartiles. (E) PaCMAP plot of NeoRED-P patient tumor-infiltrating CD4 + FoxP3 - Tconv cells by CyTOF. Clusters were derived from FlowSOM. (F) Pseudocolor density plots of CD4 Tconv cells in PaCMAP space stratified by treatment group. (G) Expression of CD39 and 4-1BB by geometric MI on CD4 Tconv as represented by color mapping on PaCMAP plot. (H) Violin plot representing frequency of manually gated CD39 + 4-1BB + CD4 Tconv cells as a percentage of all CD8 T cells stratified by treatment group. Untreated, n = 7; ADT, n = 8; ADT + anti-CTLA4-NF, n = 8. Single patient with MSI hi status called out in plot. (I) PaCMAP plot of MycCaP-infiltrating CD8 T cells by 45-parameter flow cytometry in response to ADT, ADT + anti-CTLA4 (ND), or ADT + anti-CTLA4 (D). Clusters were derived from FlowSOM. (J) Pseudocolor density plots of CD8 T cells in PaCMAP space stratified by treatment group. (K) Expression of CD39 and 4-1BB by geometric MFI on CD8 T cells as represented by color mapping on PaCMAP plot. (L) Violin plot representing frequency of manually gated CD39 + 4-1BB + CD8 T cells as a percentage of all CD8 T cells stratified by treatment group. (M) Biaxial plots representing expression of CD44 and Ki67 on CD8 T cells in tumor-draining lymph nodes of mice shown in (I–L). (N) Biaxial plots representing expression of CD44 and Ki67 on CD4 + FoxP3 − Tconv cells in tumor-draining lymph nodes of mice shown in (L–O). (O) Violin plots representing frequencies of CD44 + Ki67 + CD8 and CD4 Tconv cells as a percentage of parent populations stratified by treatment group. Two-tailed Welch’s t test was used to assess statistical significance. All murine data shown are n = 7 per group and representative of two independent experiments each for survival and immune profiling studies.

    Article Snippet: Anti-Human 4-1BB (4B4-1) 158Gd , Standard BioTools , Cat# 3158013B.

    Techniques: Derivative Assay, Expressing, Flow Cytometry, Two Tailed Test